Dr. Bhatia’s Neuro-Pain Clinic in Fresno is currently looking for individuals to participate in a cervical dystonia study. Cervical dystonia, also called spasmodic torticollis, is a painful condition in which your neck muscles contract involuntarily, causing your head to twist or turn to one side. Cervical dystonia can also cause your head to uncontrollably tilt forward or backward. A rare disorder that can occur at any age, cervical dystonia most often occurs in middle-aged people, women more than men. Symptoms generally begin gradually and then reach a point where they don’t get substantially worse.

To qualify, participants must:

  • Be 18 to 75 years of age
  • Have a diagnosis of Cervical Dystonia (Torticollis)
  • Be on a stable dose of medications

In addition,

  • Qualified participants will receive investigational medication and study-related medical care at no cost.
  • Participants may also receive compensation for time and travel.
  • No health insurance required and no overnight stays.


The muscle contractions involved in cervical dystonia can cause your head to twist in a variety of directions, including:

  • Chin toward shoulder
  • Ear toward shoulder
  • Chin straight up
  • Chin straight down

The most common type of twisting associated with cervical dystonia is when your chin is pulled toward your shoulder. Some people experience a combination of abnormal head postures. A jerking motion of the head also may occur.

Many people who have cervical dystonia also experience neck pain that can radiate into the shoulders. The disorder can also cause headaches. In some people, the pain from cervical dystonia can be exhausting and disabling.


In most people with cervical dystonia, the cause is unknown. Some people who have cervical dystonia have a family history of the disorder. Researchers have found gene mutations associated with cervical dystonia. Cervical dystonia is also sometimes linked to head, neck or shoulder injuries.

Risk factors

Risk factors for cervical dystonia include:

  • Age. While the disorder can occur in people of any age, it most commonly begins after age 30.
  • Your sex. Women are more likely to develop cervical dystonia than are men.
  • Family history. If a close family member has cervical dystonia or some other type of dystonia, you are at higher risk of developing the disorder.


In some cases, the involuntary muscle contractions associated with cervical dystonia can spread to nearby areas of your body. The most common locations include the face, jaw, arms and trunk.

People who have cervical dystonia may also develop bone spurs that may reduce the amount of space in the spinal canal. This can cause tingling, numbness and weakness in the arms, hands, legs or feet.

If you are interested in participating in this clinical research program, or would like more information, please contact our office by phone at (559) 437-9700 ext 310 (Sally), ext 312 (Janeen) or by email at research@neuropain.com.

Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. Researchers believe that fibromyalgia amplifies painful sensations by affecting the way your brain and spinal cord process painful and non painful signals.

Currently there are an estimated 6 to 12 million people who suffer from fibromyalgia. Fibromyalgia is classified as a chronic pain disorder, presenting with symptoms such as pain across the body that is difficult to treat or manage, insomnia and fatigue. This often makes it difficult to complete daily activities, such as walking short distances and using the stairs. Typically affecting women in higher numbers than men, there is also increased likelihood of developing fibromyalgia if an immediate family member has been diagnosed!

Finding appropriate treatments for fibromyalgia can be difficult, as many who have the condition often need a trial-and-error approach. This is not a one size fits all condition, requiring attentive doctors and patients alike to work together to find the right therapeutic combination.

Clinical Study: This research study is evaluating an investigational new drug to determine if it might reduce symptoms associated with fibromyalgia. Patients who enroll in this study will be asked to participate for up to 16 weeks. Study participants will be asked to take the study drug once a day. During study, participants will be randomly placed into different study groups. Two groups will receive the study drug being tested, and one group will receive a placebo. A placebo looks like the study drug, but it won’t have any effect on the person who gets it. Participants will also be asked to complete handheld study diary entries at least twice daily to track their progress throughout the study. Each person will be provided an electronic handheld device to complete this task.

Study Criteria
To participate in this study, patients must:
  • Be 18 to 75 years old
  • Have a diagnosis of fibromyalgia for more than one year
  • Discontinue pain medications for fibromyalgia and agree to use only acetaminophen, as needed, for breakthrough pain related to fibromyalgia

Other eligibility criteria apply. Study participants receive study-related medical exams and study drug at no cost. Compensation for time and travel is available.

Importance of Clinical Trials:

Clinical research studies, also known as clinical trials, are designed to answer specific questions about study drugs and are needed to help find new and possibly better future treatments for diseases. A study drug goes through several phases of clinical research to evaluate its safety and effectiveness. Depending on the results of the research, the study drug could later be available to the public. An external review board made up of doctors, ethicists, members of the general public, and administrators help to ensure that a clinical trial does not present an unreasonable risk to individuals who are participating. Your own doctor is responsible for your well-being and you may speak with him or her to discuss clinical trial participation before you decide to join. Whenever you agree to enter a clinical trial, you are given the name and telephone number of a contact in your study doctor’s office who will answer any questions you may have.

For many people, taking part in a clinical trial is important because their participation is helping to make new treatments possible.
If you are interested in participating in this clinical research program, or would like more information, please contact our office by phone at (559) 437-9700 ext 310 (Sally), ext 312 (Janeen) or by email at research@neuropain.com.

Excessive daytime sleepiness (EDS) is described as inappropriate and undesirable sleepiness during waking hours and is a common non-motor symptom in Parkinson’s disease, affecting up to 50% of patients. EDS has a large impact on the quality of life of Parkinson’s disease patients as well as of their caregivers, in some cases even more than the motor symptoms of the disease. Drug-induced EDS is a particular problem as many dopamine agonists used for the treatment of Parkinson’s disease have EDS as an adverse effect.


We are pleased to announce a new clinical research program that is occurring at our facility. This special opportunity may be beneficial for you or for someone you know. It involves patients with Parkinson’s disease and excessive sleepiness.

If you qualify, you could receive medication to potentially help with your excessive sleepiness. The patient will be compensated for travel expenses only after qualifying for the study. All the relevant physical examination, blood tests, EKGs, and study assessments are completed at no cost. If you are interested in participating in this clinical research program, or would like more information, please contact our office by phone at (559) 437-9700 ext 310 (Sally), ext 312 (Janeen) or by email at research@neuropain.com

If you have any questions or concerns, please feel free to contact our office. We will be happy to provide additional study information.

If you have diabetes and shooting, burning, pins and needles pain in your feet or hands, you could have painful diabetic peripheral neuropathy—also known as diabetic nerve pain (DNP). It is a common complication of diabetes. The most common cause is poorly controlled blood sugar over time. High blood sugar (glucose) can injure nerve fibers throughout your body, but diabetic neuropathy most often damages nerves in your legs and feet.

Diabetic nerve pain can take years to develop. In the early stages, you may have no signs at all, and then only start to feel a tingling or numbness in your feet. As it progresses, you may also feel the pain in your hands and it is often worse at night. This means that your nerves may be damaged for a long time before you experience painful symptoms.

A clinical research study and trial is being conducted to review the efficacy and safety of an investigation drug NYX-2925. Dr. Bhatia’s Neuro Pain Clinic is one of the 35 centers in the United States conducting this clinical trial and is actively recruiting patients who have Type 2 diabetes and have pain associated with diabetic peripheral neuropathy. The trial will last about 6 to 9 weeks, and all eligible patients will receive study related care and study related drugs at no cost.

Who can participate in the study?

  • Type 2 Diabetes patients
  • Have pain associated with diabetic peripheral neuropathy in the feet and/or legs, and
  • Between the age  of 18 to 70 years

How is this study evaluated?

Participating patients will be randomly assigned to the study drug. Some patients will receive investigational drug and some will receive a sugar pill called a placebo. To find out, how well the investigational drug works, Dr. Bhatia will assess participant’s pain at different points throughout the study by measuring, for example:

  • Pain intensity
  • Pain when walking
  • Effect of pain on sleep

The trial will also determine the safety of the investigational drug by studying side effects by measuring vital signs, 5-minute electrocardiogram, and clinical lab tests on blood and urine.

To learn more about this clinical trial, please visit the FDA website or contact our research team.


The Alzheimer’s DAYBREAK-ALZ Study is a clinical research study for people with memory problems or mild Alzheimer’s disease. We are looking for people who would like to participate.

Alzheimer’s is a type of dementia that causes problems with memory, thinking and behavior. Symptoms usually develop slowly and get worse over time, becoming severe enough to interfere with daily tasks. As we get older, most of us become more forgetful. Keys go missing, we can’t remember names easily, memories fade. But if you find that forgetfulness is becoming a problem for you, people comment on your memory loss, or you have difficulty planning or problem-solving, these could be early signs of Alzheimer’s disease.

Alzheimer’s disease is very common, it affects one in 1,400 who are age 40-64 years, one in 100 people age 65-69 years, one in 25 of people in their 70s, and one in 6 of people age 80 years or older.

Symptoms of Alzheimer’s disease include memory loss, difficulties thinking, problem-solving and communicating. Alzheimer’s disease develops due to changes in the structure and chemistry of the brain that affect its ability to function properly when performing certain “mental” activities. This is known as cognitive impairment.

Alzheimer’s has no current cure, but treatments for symptoms are available and research continues.

Although current Alzheimer’s treatments cannot stop Alzheimer’s from progressing, they can temporarily slow the worsening of dementia symptoms and improve quality of life for those with Alzheimer’s and their caregivers.

Dr. Bhatia’s clinic is conducting Alzheimer’s DAYBREAK-ALZ Study in Fresno

Do you or a loved one have memory problems or mild Alzheimer’s disease?

Then you may be interested in the DAYBREAK-ALZ clinical research study.

  • The DAYBREAK-ALZ study is a clinical research study for people with memory problems or mild Alzheimer’s disease.
  • The study will examine if an investigational medication, taken by mouth, may slow the decline in memory and mental functioning associated with Alzheimer’s.
  • There is no cost to participate. Volunteers who take part in the study will receive all study-related care, from a Specialist Physician, at no cost and you may be compensated up to $150 per visit for your time and travel expenses.

Who can join the DAYBREAK-ALZ Study?

To join the study you must:

  • Be between 55 and 85 years old
  • Have a close friend, relative or partner who would be willing to be your study partner throughout the study
  • Have experienced a gradual loss of memory over the last 6 months (the study team will assess whether this is due to Alzheimer’s disease) or have been diagnosed with mild Alzheimer’s disease


If you think you might like to join the DAYBREAK-ALZ study or you would like to learn more, please contact us. We can tell you more about it and explain what participating would mean for you. We will talk through the potential benefits and risks of being involved in the study, before you make your decision about joining.

We will also carry out several medical checks to see whether you are right for the study, and the study is right for you.

What does the study involve?

The study will last for around three years – 8 weeks to see if you qualify, plus 3 years of treatment, then 4 weeks of follow-up.

The study drug is a tablet, to be taken once a day. The tablet will contain either a lower dose of the study drug, a higher dose of the study drug, or a placebo, depending on which group you are assigned to. A placebo tablet is one that contains no active ingredients.

You will be assigned at random to one of the study groups. Neither you nor the study doctor will know which group you’ve been assigned to. There is a 2 in 3 chance that you will receive the study drug. If it is necessary to find out which group you’ve been assigned to, the study doctor can do so quickly.

You will need a study partner. This person needs to be someone who you are in regular contact with, who will go with you to study appointments, and who can help the study team to notice any changes in your mental functioning.

If you join the study, you and your study partner will be asked to attend around 29 appointments. During these appointments, we will assess your health, thinking and memory with some standard medical tests and questionnaires. We will also ask you about any side effects you may experience. These appointments will be every 3 weeks for the first few visits and then every 7 weeks until the end of the study.


Chronic low back pain affects most adults, causes disability for some, and is a common reason for seeking healthcare. In the United States, opioid prescription for low back pain has increased, and opioids are now the most commonly prescribed drug class. More than half of regular opioid users reported back pain. America’s opioid crisis is taking the life of a person every 19 minutes. Responding to this crisis, Braeburn Pharmaceuticals has launched Phase 3 clinical trial for long lasting Buprenorphine injection.

Dr. Bhatia’s Neuro Pain Medical Center (located in Fresno, CA) is conducting a clinical research for low back pain. Qualified volunteers must:

  • Be 18-75 years old
  • Currently taking high doses of an opioid for low back pain
  • Have 3+ months of diagnosis of low back pain

If selected, the volunteers will receive long lasting investigational pain medication (Buprenorphine) injection and morphine as rescue medication. This is a no-cost to patient trial, so insurance is not required. Selected volunteers will receive free assessment, medicine and examination, and will also be compensated for travel.



Low back pain is common. Almost everyone has back pain at some time in their life. Often, the exact cause of the pain cannot be found.

A single event may not have caused your pain. You may have been doing many activities, such as lifting the wrong way, for a long time. Then suddenly, one simple movement, such as reaching for something or bending from your waist, leads to pain.

Many people with chronic back pain have arthritis. Or they may have extra wear and tear of the spine, which may be due to:

  • Heavy use from work or sports
  • Injuries or fractures
  • Surgery

You may have had a herniated disk, in which part of the spinal disk pushed onto nearby nerves. Normally, the disks provide space and cushion in your spine. If these disks dry out and become thinner and more brittle, you can lose movement in the spine over time.

If the spaces between the spinal nerves and spinal cord become narrowed, this can lead to spinal stenosis. These problems are called degenerative joint or spine disease.

Other possible causes of chronic low back pain include:



A migraine can cause severe throbbing pain or a pulsing sensation, usually on just one side of the head. It’s often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. Headaches can vary between from being a minor aggravation to a severe and incapacitating pain. It can be difficult to identify whether an individual is suffering from a mild headache or a migraine, which is a neurological disease, affecting 38 million men, women and children in the United States. Consequently, it is essential to emphasize the distinction between a migraine and a headache as it leads to rapid relief with effective treatments. Fresno migraine specialist Dr Bhatia’s Neuro Pain Medical Center located on Bullard Ave, Fresno is conducting an advanced clinical research study on migraine attacks.

A headache is in which blood vessels constrict and dilate, thus releasing inflammatory substances that cause painful pulsations. A chronic headache is accompanied by mild to severe pain commonly occurring on both sides of the head for more than four hours on more than 15 days per month. Assertive initial treatment coupled with continuing management may well reduce pain and result in fewer headaches in the future. Conversely, a migraine headache is the outcome of definite physiologic changes that take place within the brain and result in distinctive pain with the combined symptoms.



Migraines often begin in childhood, adolescence or early adulthood. Migraines may progress through four stages: prodrome, aura, headache and post-drome, though you may not experience all stages.
One or two days before a migraine, you may notice subtle changes that warn of an upcoming migraine, including:

• Constipation
• Mood changes, from depression to euphoria
• Food cravings
• Neck stiffness
• Increased thirst and urination
• Frequent yawning

The most common migraine symptoms are:

• Throbbing, pulsating pain – 85 percent
• Light sensitivity – 80 percent
• Sound sensitivity – 76 percent
• Nausea – 73 percent
• Pain on one side – 59 percent
• Vision changes, blurred vision – 44 percent
• Aura – 36 percent
• Vomiting – 29 percent
(Note: These figures are from the American Migraine Study II of almost 4,000 migraine sufferers in 1999)

Fresno Migraine Specialist Dr. Bhatia has Treatment options:

As a matter of fact, most of the people will encounter a headache sooner or later in their lives. However, there are people who deal with more lasting and severe headaches and migraines than others. The Neurologist Dr. Bhatia based in Fresno, CA offers top notch medical care for neurological conditions and also recruits patients for migraine study and research.

You can also apply to qualify for a free Migraine-based research study. The goal of clinical trials is to determine if a new test or treatment works and is safe. The advanced studies done during clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. If you are experiencing migraines or know a friend or family with migraine issues, you can refer them to our clinic.

The center offers a wide-ranging treatment to patients suffering with chronic headache and migraine in Fresno, CA. You will get the right help at the right time with the Neuro Pain Medical Center’s online available team catering to appointments, referrals, RX refills, and clinical trials.

Fresno migraine specialist Dr Bhatia
Fresno migraine specialist Dr Bhatia


Have your previous Migraine medications failed you?

You may qualify for a research study (Clinical Trial Phase 3) if you:

  • Have 2-8 moderate/sever migraine attacks per month
  • Have had migraines for at least a year, and
  • Between 18 -75 years of age

Qualified participants may receive:

  • Study related care and examination at no cost
  • Compensation for time & travel

Please use the form below at the bottom of the website to receive alerts from our clinic or use the contact form here.

This study can last from 1-4 months to treat a single migraine attack.  Participants must have 2-8 migraine attacks per month, and can be on preventive migraine treatment if they are stable over the last 2 months. Participants will have the option of rolling into the 18 month long-term study.

Clinical trials are part of clinical research and at the heart of all medical advances. Clinical trials look at new ways to prevent, detect, or treat disease.

The goal of clinical trials is to determine if a new test or treatment works and is safe. The advanced studies done during clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. If you are experiencing migraines or know a friend or family with migraine issues, please refer them to our clinic.

Please visit the FDA website for more details on this trial – https://clinicaltrials.gov/ct2/show/NCT02867709


Clinical trials for Neurological Conditions

Clinical trials are essential to determine whether new drugs, diagnostics or procedures in the laboratory are both safe and effective when used to diagnose or treat people.Our office is recruiting patients for following clinical trials. Please remember that we do not bill for these studies to the insurance company, so it does not matter whether the patient is insured or not insured.

  1. Osteoarthritis of Hip or Knee
  2. Chronic Low back pain
  3. Moderate Alzheimer’s disease: MMSE 10-20 Pt on Namenda and Aricept.
  4. Any memory impairment, for Amyloid PET scan Evaluation (Medicare patients only)
  5. Complex partial/ Focal Epilepsy- Open label study
  6. Moderate advanced Parkinson’s disease
  7. Acute Migraine
  8. Chronic Migraine
  9. Agitation in Alzheimer’s disease
  10. Mild Alzheimer’s disease- Day Break study
  11. Stem cell treatment for stroke- chronic deficit
  12. Psychosis in Parkinson’s disease

Carefully conducted clinical trials are performed in human volunteers to provide answers to questions such as:
– Does a treatment work?
– Does it work better than other treatments?
– Does it have side effects?

If you would like to learn more about the clinical trial process, please visit our Research page.

Patient Safety:

We collaborate with regulatory agencies, monitor reports of adverse events experienced by patients and communicate on our product safety activities, as appropriate to the audience. Any medicine may cause side effects in some patients. Our priority is to make sure that the therapeutic benefits of the medicine outweigh the risks


Our office is recruiting patients for the following clinical trials:

  1. Osteoarthritis of Hip or Knee
  2. Chronic Low Back Pain
  3. Moderate Alzheimer’s disease MMSE 10-20 Pt on Nameda and Aricept
  4. Any memory impairment, for Amyloid PET Scan Evaluation (Medicare patients only)
  5. Epilepsy – Open label study
  6. Cluster Seizures
  7. Acute Migraine
  8. Chronic Migraine
  9. Agitation in Alzheimer’s disease
  10. Mild Alzheimer’s Day break study

You can learn more about the clinical trial process here: http://neuropain.com/research/

If you have any questions, please contact: http://neuropain.com/contact/

This website is for informational purposes only. Please dial 911 for emergency.

Torticollis Research Study
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